Though it is unlikely that any one marker could function as a true surrogate or stand alone biomarker combinations or patterns could provide insight into the mechanism of action of a drug and could suffice for the pre screening of prospective therapeutics this publication examines the potential of biomarkers in the context of ms. Biomarkers in multiple sclerosis book edition of disease markers available in paperback add to wishlist isbn 10 1586036971 isbn 13 9781586036973 pub date 11 15 2006 publisher i o s press incorporated biomarkers in multiple sclerosis book edition of disease markers by u utz surrogate or stand alone biomarker combinations or . During the last decades the effort of establishing satisfactory biomarkers for multiple sclerosis has been proven to be very difficult due to the clinical and pathophysiological complexities of the disease recent knowledge acquired in the domains of genomics immunogenetics and neuroimmunology as . Disease markers 22 2006 183 185 183 ios press introduction biomarkers in multiple sclerosis roland martina bibiana bielekovab reinhard hohlfeldc and ursula utzd acatalan institute for research and advanced studies and unidad de neuroimmunologia clinica hospital universitari vall dhebron barcelona spain. Substantial effort has been made over the last six decades to identify biomarkers for multiple sclerosis that can improve disease diagnosis predict disease progression and improve clinical outcomes however to date few of these findings have proven clinically useful in this review we address the current state of ms biomarker research
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