Some people with hemophilia and von willebrand disease vwd type 3 will develop inhibitors inhibitors make it more difficult to stop a bleeding episode because they prevent the treatment from working if you have hemophilia or vwd type 3 it is important to be tested for inhibitors once a year . In patients with persistent inhibitors if bleeding into the muscles and joints the most common type of bleeding in hemophilia is not controlled permanent joint damage is likely for people with sufficient access to care treatment of inhibitors is one of the biggest challenges in hemophilia today. The goal of this activity is to discuss the latest advances in the understanding of inhibitors in patients with hemophilia a including the risks associated with inhibitors as well as current and new approaches to management. Factor viii fviii replacement therapy is the foundation of treatment in hemophilia a and is effective unless a patient develops an alloantibody inhibitor against exogenous fviii inhibitor development is currently the most significant treatment complication seen in patients with hemophilia and . In spite of recent major advances in the understanding and treatment of inhibitor development in patients with haemophilia multidisciplinary management of many of these patients remains suboptimal and highly heterogenous across europe following a series of multidisciplinary meetings and a review of the literature the european haemophilia community of health professionals and patients
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