In this volume supportive care in cancer therapy a part of the cancer drug discovery and development series the contributors provide an up to date concise review of specific consequences of cancer and its treatment. The discovery and development of new therapeutic agents for cancer is essential for continued progress against the disease historically nci has played a vital role in cancer drug discovery and development and today that role continues frequently ncis drug development efforts focus on unmet . The program supports research in three areas prevention or treatment of acute or chronic symptoms and morbidities related to cancer its treatment and caregiving symptom management research effects on quality of life from cancer its treatment and caregiving quality of life research and end of life psychosocial issues caregiving and treatment strategies end of life. Post clinical research which takes place after the drug is approved drug discovery and initial testing the discovery of new cancer drugs can happen in different ways accidental discovery in the early 1940s an explosion exposed sailors to poisonous mustard gas doctors found that these sailors had low white blood cell counts. Prevent cancer preclinical drug development program prevent program to assess the rigor and reproducibility of exosome derived analytes for cancer detection prostate lung colorectal and ovarian cancer screening trial plco small cell lung cancer sclc consortium supportive care and symptom management translational liver cancer tlc
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